Doxazosin
Dosages;
Combinations; See below
Doxazosin Brands
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Ltd. | Ltd | mg | 30 | Tablet | per tablet | KES | |
| Ltd | (K) Ltd. | mg | 30 | Tablet | per tablet | KES |
| Doxazosin More info | |
|---|---|
| Mode Of Action | Blocks postsynaptic alpha-1-receptors |
| Drug Indication | Hypertension; benign prostatic hyperplasia. |
| Precautions | Care with initial dose (postural hypotension); pulmonary oedema due to aortic or mitral stenosis; cataract surgery (risk of intra-operative floppy iris syndrome); heart failure; Driving: may affect performance of skilled tasks e.g. driving |
| Contra-Indications | Hypersensitivity, history of postural hypotension; monotherapy in overflow bladder or anuria; hepatic impairment: use with caution and avoid in severe impairment; pregnancy: no evidence of teratogenicity but use only when potential benefit outweighs risk; breast-feeding: accumulates in milk avoid. |
| Side Effects | Dyspnoea, coughing; fatigue, vertigo, paraesthesia, sleep disturbance, anxiety; influenza-like symptoms; back pain, myalgia; less commonly weight changes, angina, myocardial infarction, hypoaesthesia, tremor, agitation, micturition disturbance, epistaxis, arthralgia, tinnitus, and gout; very rarely cholestasis, hepatitis, jaundice, bradycardia, arrhythmias, bronchospasm, hot flushes, gynaecomastia, abnormal ejaculation, leucopenia, thrombocytopenia, and alopecia. |
| Dosage | Hypertension, 1 mg daily, increased after 1-2 weeks to 2 mg once daily, and thereafter to 4 mg once daily, if necessary; max. 16mg daily. |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Alpha-adrenoceptor blocking agents |